Tutorials

Here we present different case studies and usages of the IntraTalker package.

• Case study: Il1rn knockout bone marrow
  • Workflow Overview
  • Inter- and Intracellular Communication
  • Gene Expression Perturbations
  • Citation

Available tutorials

Il1rn knockout bone marrow — the full pipeline on murine bone marrow (Villatoro et al.): ligand–receptor inference, transcription factor activities, the receptome, communication communities, and in silico receptor knockouts recovering Il1r1 as a driver of MSC differentiation.

Parts of this workflow use the R packages LR2TF and CrossTalkeR