# Tutorials

Here we present different case studies and usages of the IntraTalker package.

```{toctree}
:maxdepth: 2

il1rn_bone_marrow/index
```

## Available tutorials

**[Il1rn knockout bone marrow](il1rn_bone_marrow/index.md)** — the full pipeline on murine bone
marrow (Villatoro et al.): ligand–receptor inference, transcription factor activities, the
receptome, communication communities, and *in silico* receptor knockouts recovering Il1r1 as a
driver of MSC differentiation.

Parts of this workflow use the R packages
[LR2TF](https://github.com/CostaLab/LR2TF) and
[CrossTalkeR](https://github.com/CostaLab/CrossTalkeR)