scMEGA (Single-cell Multiomic Enhancer-based Gene regulAtory network inference) is a R package designed to infer gene regulatory network by using single cell multi-omics data. It is based on several popular packages for single cell RNA/ATAC-seq data analysis, particularly, Seurat, Signac, and ArchR. Picture below showed the principal of scMEGA for linking genes to TFs and building a gene regualtory network.